Prenatal diagnosis of mosaic 4p – in a fetus with trisomy 21

Mosaicism for the Wolf-Hirschhorn syndrome, del(4)(p16), is extremely rare and has not been reported in association with a numerical chromosome abnormality. We report the prenatal diagnosis of mosaic del(4)(p16) and non-mosaic trisomy 21 in a 16-week female fetus. The pregnancy ended in spontaneous abortion at 34 weeks secondary to fetal demise. The fetus had features of both 4p – and trisomy 21.     

The promissory note: COP 21 and the Paris Climate Agreement

The 2015 UN climate negotiations in Paris resulted in an inclusive, binding treaty that succeeds the Kyoto Protocol. In contrast to the failure at Copenhagen in 2009, the Paris negotiations are therefore seen as a major diplomatic success that has regenerated faith in the United Nations Framework Convention on Climate Change as a forum for dynamic multilateralism. The Paris Agreement provides a robust framework for ratcheting up efforts to combat global warming. However, the Agreement’s value will remain unclear for some time. The historical path to the Paris accord is outlined, and a preliminary assessment is offered of its key elements and outcomes.     

Xα21基因导入水稻及转基因植株的鉴定

以水稻愈伤组织为受体、质粒pCXK1301为Xα21基因供体,用农杆菌EHA105和PDS－1000／He基因枪转化受体,经Hyg浓度梯度筛选,获得一些转基因水稻植株,GUS检测、PCR扩增和Southern杂交分析表明,报告基因（GUS）、选择标记基因（Hyg^r）和抗白叶枯病基因Xα21都已整合入转化水稻基因组中,Southern杂分析显示了Xα21基因在转化水稻基因组中整合的拷贝数。田间接菌鉴定表现抗白叶枯病。     

《21世纪议程》:行动与展望

1992年,联合国环境与发展大会通过了《关于环境与发展的里约热内卢宣言》、《21世纪议程》和《关于森林问题的原则声明》3项重要文件。之后,国际社会为推动"里约精神"的落实做出了积极努力:联合国可持续发展委员会每年举行会议,审议《21世纪议程》的执行情况;许多国家制定了国家和地方层面的《21世纪议程》或可持续发展战略;相关国际组织以可持续发展能力建设为主的活动也十分活跃。人类把发展与环境相协调作为行动准则,各国依据国情制定了促进环境与发展相协调的优先事项,使人类在实现可持续发展的进程中取得了积极进展:全球经济实现了大幅增长,发展中国家在全球经济格局中的地位不断上升;在消除贫困等社会发展方面取得显著效果,全球开始进入城市化时代;全球能源资源供应呈现多元化,资源节约集约利用成效显著。中国在经济发展滞后、贫困现象较严重背景下,承担了全球实施《21世纪议程》的旗舰角色;并依据本国的具体国情,选择性地学习与借鉴,摸索创造出具有自身特色的发展模式和道路,增加了世界可持续发展方式选择的多样性。20年来,尽管各个国家在可持续发展方面采取了积极行动,但是"里约精神"尚未全面转化为行动,在相关国际承诺与公约的履行方面还需付出巨大努力,仍然面临着重大挑战。如:以气候变化为代表的重大全球性环境问题对人类生存构成的直接威胁加大;生态超载背景下的发展空间争夺更趋激烈;全球性民生问题凸显,可持续发展面临的社会风险加大,等等。我们期待:通过"里约+20"大会,使得相关国际制度安排不断形成和完善,可持续发展进一步向全球行动转化;科技创新步伐加快,进一步推动全球向绿色发展转型;加快全球治理体系调整,新兴发展中国家成为全球可持续发展的重要推动力;全球共同努力解决重大资源环境问题,可持续发展领域的国际关系呈现竞争性合作。     

21世纪住区建设

面对世界发展趋势和中国建设高潮期,21世纪住宅建设需体现可持续发展,引入信息技术和新材料等高新技术,适应居住生活的发展。本文概述了当前世界发展趋势和国家住宅建设目标,住宅建设面临的科技问题,着重论述21世纪住区建设的规划设计原则。     

SUSTAINABILITY AT THE LOCAL LEVEL: MANAGEMENT TOOLS AND MUNICIPAL TAX INCENTIVE MODEL

The implementation of sustainable development may seem a simple concept when written on paper. However to carry-out long term actions put forward by the Agenda 21 (AG21) at the local level represents one of the main challenges as municipal governments in general do not have the capacity to effectively implement the process. Regional environmental assessment (REA) has shown to be effective in supporting decision-making not only to correct environmental problems due to past unsustainable social-economic developments but also help local governments to implement sustainable actions. However this requires long-term investments of AG21 plans and projects. The allocation of regular and consistent financial resources is one of the main ingredients for the sustainable development process. But traditional plans and projects financed by national and/or international funds may not be sustainable in the long-term because they become dependent on external funding. Research demonstrate that innovative economic instruments such as ecotaxes represent a feasible alternative to sponsor local sustainability because taxes are collected permanently by the government and could be invested in continuous actions. Ecotaxes experiences have provided important reference to structure a municipal incentive model (MIM) to sponsor AG21’s environmental plans and projects on a long-term (permanent) basis. However sustainable development cannot be solely through economic investments. A comprehensive municipal environmental management scheme (MEMS) has been established to support the incentive model. The scheme seeks not only to improve local institutional framework but also incentive continuous participation of local stakeholders at all levels of society. Participatory events and the provision of incentives (educational and financial) are key to motivate society to protect the environment and support actively the sustainable development process as emphasised in the RIO-92 Conference.