Clinical aspects of static magnetic field effects on circulatory system |
| |
Authors: | Chiyoji Ohkubo Hideyuki Okano |
| |
Institution: | (1) Japan EMF Information Center, Tokyo, Japan;(2) Meiji Pharmaceutical University, Tokyo, Japan;(3) Research Center for Frontier Medical Engineering, Chiba University, Chiba, Japan;(4) Product Development Division, R&D Section, PIP Co., Ltd., Osaka, Japan |
| |
Abstract: | Increased knowledge of the magnetic field influence on hemodynamic function may have significant therapeutic potential and
possible health effects. For example, magnetic field therapy using moderate intensity static magnetic fields (SMF) in the
mT range (in particular, 1–600 mT) could be useful for circulatory diseases, including ischemic pain, inflammation, and hypertension,
primarily due to the modulation of blood flow and/or blood pressure through the nervous system. We suggested that the mechanisms
of SMF effects on the circulatory system in the mT range could be mediated by suppressing or enhancing the action of biochemical
effectors, thereby inducing homeostatic effects biphasically. The potent mechanisms of SMF effects have often been linked
to nitric oxide pathway, Ca2+-dependent pathway, sympathetic nervous system (e.g., BRS and the action of sympathetic agonists or antagonists), and neurohumoral
regulatory system (e.g., production and secretion of angiotensin II and aldosterone). Thus, this review mainly focuses on
the experimental studies of SMF effects on the circulatory system in animals and may provide the physiological basis for future
clinical investigations of SMF therapy. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|