Persistent organic pollutants and heavy metals in adipose tissues of patients with uterine leiomyomas and the association of these pollutants with seafood diet, BMI, and age |
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Authors: | Yan Yan Qin Clement Kai Man Leung Anna Oi Wah Leung Sheng Chun Wu Jin Shu Zheng Ming Hung Wong |
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Affiliation: | (1) Croucher Institute for Environmental Sciences and Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong, SAR, People’s Republic of China;(2) IVF Centre Limited, Hong Kong Sanatorium and Hospital, 2 Village Road, Happy Valley, Hong Kong, SAR, People’s Republic of China; |
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Abstract: | Background, aim, and scope Persistent organic pollutants and heavy metals can cause diseases in women, however, the relationships of these pollutants and uterine leiomyomas (UL), which are non-cancerous tumors of the uterus, are unclear. This study focused on the quantification of organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs), and heavy metals in subcutaneous and visceral fat obtained from patients with UL and in subcutaneous fat of a control group of women without UL to determine if there were any correlations between concentrations of persistent organic pollutants (POPs) and heavy metals and the incidence of UL. |
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