Transplacental transfer of phenyltins from a pregnant Dall's porpoise (Phocoenoides dalli) to her fetus |
| |
Authors: | Yang Jian Harino Hinoya Miyazaki Nobuyuki |
| |
Institution: | Key Laboratory of Ecological Environment and Resources of Inland Fisheries, Freshwater Fisheries Research Center, Chinese Academy of Fishery Science, Qitang Road No. 1, Wuxi City, Jiangsu 214081,China. yangj@ori.u-tokyo.ac.jp |
| |
Abstract: | The maternal to fetal transfer of monophenyltin (MPT), diphenyltin (DPT), and triphenyltin (TPT) was investigated for the first time in a cetacean species, a mother-fetus pair of Dall's porpoises (Phocoenoides dalli) collected off the Sanriku coast, Japan. The mother individual was contaminated by phenyltin compounds, and the muscle, blubber, and liver accounted for 90% of the total phenyltin burden. A two-generation phenyltin contamination via transplacental transfer was demonstrated. This study revealed that the transfer rate was 0.29% for total phenyltins to a fetus of about 6-month-old. Unlike in the mother, the fetal liver could not be considered the target organ for all the phenyltins studied. In a ca. 100kg-weight mother Dall's porpoise and its fetus of 2.21kg-weight, approximately 153microg (TPT, 139microg; DPT, 9.4microg; MPT, 4.2microg) and 0.44microg of total phenyltins (TPT, 0.38microg; DPT, 0.03microg; MPT, 0.03microg) were found, respectively. The body burden of TPT consisted of 91% and 86% of the total phenyltin burdens in the maternal and fetal bodies, respectively. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|