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The antifungal activity of the leaf gland volatile oil of sweet gale (Myrica gale) (Myricaceae)
Authors:Robert R. Carlton  Peter G. Waterman  Alexander I. Gray  Stanley G. Deans
Affiliation:(1) Phytochemical Research Laboratories, Department of Pharmacy, University of Strathclyde, G1 1XW Glasgow, United Kingdom;(2) Department of Biological Sciences, Scottish Agricultural College, KA6 5HW Auchincruive, Ayr, United Kingdom;(3) Present address: Environmental Sciences Department, Schering Agrochemicals Ltd, Chesterford Park Research Station, CB10 1XL Saffron Walden, Essex, United Kingdom
Abstract:Summary The antifungal activity of volatile oil obtained from the leaves of sweet gale (Myrica gale) has been investigated. Fungi, isolated from the leaves ofM. gale, were grown in liquid medium containing the oil and its effect on biomass production was gauged. The oil inhibited growth of all species of fungi to greater or lesser extent. Sesquiterpenes were more active than monoterpenes, and among the sesquiterpenes germacrone was marginally more active than beta-elemenone. These results support the proposition that the volatile oil ofM. gale has a role in resistance to fungal pathogens.
Keywords:chemical defenses  antifungal activity  volatile oil  terpenes  Myriaceae  Myrica gale
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