Neurotransmitter level changes in domestic ducks(Shaoxing duck) growing up in typical mercury contaminated area in China |
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Authors: | JI Xiu-ling YANG Liu SHEN Zhe-min CHENG Jin-ping JIN Gui-wen QU Li-ya and WANG Wen-hua |
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Institution: | 1. School of Environmental Science and Engineering, Shanghai Jiaotong University, Shanghai 200240, China 2. Guizhou Institute for Environmental Protection, Guiyang 550002, China |
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Abstract: | The neurotransmitter level changes of ducks exposed 8-month in a mercury-polluted site(Wanshan, China) and a reference site(Shanghai, China) were examined. Chemical analyses showed both higher mercury and selenium concentrations in the organ of Wanshan ducks. An increased content of acetylcholine(ACh) in brain and blood and a decreased activity of acetylcholinesterase(AChE) in blood were observed. Moreover, there was an increasing trend for nitric oxide synthase(NOS) activity and nitric oxide(NO) production in duck brain, but a reduction of NOS activity in duck serum. The possible explanations were due to the interactive effect of selenium accumulation and the sublethal exposure level of mercury in Wanshan area. The present study showed that AChE and NOS were sensitive to mercury contamination of real circumstance, suggesting that these two indexes have the potential to be biomarkers in assessment of health effects by mercury contamination. |
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Keywords: | mercury neurotransmitter long-term exposure Wanshan area |
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