| 83—1除草剂在大鼠体内的代谢研究 |
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| 引用本文： | 喻凯,孙棉龄.83—1除草剂在大鼠体内的代谢研究[J].四川环境,1993,12(4):43-47. |
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| 作者姓名： | 喻凯 孙棉龄 |
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| 作者单位： | 华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学公共卫生学院 成都 610041，成都 610041，成都 610041，成都 610041，成都 610041 |
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| 摘 要： | 目前，我国对新农药的登记要求对其进行代谢降解研究。为此本文采用ＨＰＬＣ、ＵＶ、ＩＲ和ＭＳ等现代仪器分析的方法，给大鼠经口染毒８３－１除草剂后，在大鼠尿中分离和鉴定出四种代谢代物，发现该除草剂在大鼠体内的代谢主要是还原和结合作用。从而推断了该农药在大鼠体内的代谢转化过程。
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| 关 键 词： | 83－1除草剂 代谢 高效液相色谱 大鼠 |
Study on Metabolism of Herbicide 83-1 in Rats |
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| Yu Kai Sun Mianling Wu Desheng Luo Yongyi Sun Aimin.Study on Metabolism of Herbicide 83-1 in Rats[J].Sichuan Environment,1993,12(4):43-47. |
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| Authors: | Yu Kai Sun Mianling Wu Desheng Luo Yongyi Sun Aimin |
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| Institution: | The West China University of Medical Sciences |
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| Abstract: | The metabolism of Herbicide 83-1 was studied in rats in vivo. After oral administration of the herbicide, four ultimate metaholites were isolated and identified from urine by means of HPLC, UV, IR and MS. It was found that the metabolic reactions of the herbicide in rats were reduction and conjugation. The metabolic pathway of the herbicide in rats was deduced. |
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| Keywords: | Herbicide 83-1 metabolism HPLC |
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