| Study on the action and mechanism of humic acids in Kaschin-Beck disease |
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| 引用本文： | Wang Weizhe,Yang Zhiwei,You Shengzhi. Study on the action and mechanism of humic acids in Kaschin-Beck disease[J]. 环境科学学报(英文版), 1991, 3(4): 87-94 |
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| 作者姓名： | Wang Weizhe Yang Zhiwei You Shengzhi |
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| 作者单位： | Wang Weizhe，Yang Zhiwei and You Shengzhidepartment of Pathophysiology.Liaoning Institute of Basic Medicine.Shenyang.China |
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| 摘 要： | Humic acids, especially FA in fractions, contain more oxygen functional groups. In this experiment, on the basis of confirming the action of humic acids on KBD, what was studied is the biological effects of one of main oxygen functional groups, hydroxy group (-OH). The results indicate that inducing pathologic process of KBD, obviously decrease the GSH-Px activity and induce peroxidation membrane injury of tissue. The SOD activity increase in the tissues caused by oxygen functional groups showed that enhancing of free radical reaction should not be neglected.
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| 关 键 词： | Kaschin-Beck disease humic acids oxygen functional groups free radical antioxidase. |
| 收稿时间： | 1991-07-11 |
Study on the action and mechanism of humic acids in Kaschin-Beck disease |
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| Wang Weizhe,Yang Zhiwei and You Shengzhi. Study on the action and mechanism of humic acids in Kaschin-Beck disease[J]. Journal of environmental sciences (China), 1991, 3(4): 87-94 |
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| Authors: | Wang Weizhe Yang Zhiwei You Shengzhi |
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| Affiliation: | Wang Weizhe,Yang Zhiwei and You Shengzhidepartment of Pathophysiology.Liaoning Institute of Basic Medicine.Shenyang.China |
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| Abstract: | Humic acids, especially FA in fractions, contain more oxygen functional groups. In this experiment, on the basis of confirming the action of humic acids on KBD, what was studied is the biological effects of one of main oxygen functional groups, hydroxy group (-OH). The results indicate that inducing pathologic process of KBD, obviously decrease the GSH-Px activity and induce peroxidation membrane injury of tissue. The SOD activity increase in the tissues caused by oxygen functional groups showed that enhancing of free radical reaction should not be neglected. |
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| Keywords: | Kaschin-Beck disease humic acids oxygen functional groups free radical antioxidase. |
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