Afrikanische Trypanosomen |
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Authors: | Hans-J Risse |
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Institution: | 1. Institut für Veterin?rbiochemie der Freien Universit?t, D-1000, Berlin
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Abstract: | African trypanosomes have developed protective mechanisms in order to escape from their hosts' immune attack. New cell surface antigens become sequentially expressed during a chronic infection providing the parasites continuously with immunologically altered faces. The trypanosomal genome contains a considerable repertoire of different genes coding for the surface antigens; they become separately activated and expressed by a variety of novel molecular processes. In addition, the trypanosomal cell surface participates in the protection of the parasites against non-immune defense mechanisms of the host. |
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