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| 镉对性未成熟鸡卵巢FSHR与LHRmRNA表达的影响 | |
| 引用本文： | 杨淑华.镉对性未成熟鸡卵巢FSHR与LHRmRNA表达的影响[J].环境科学学报,2008,28(1):138-141. |
| 作者姓名： | 杨淑华 |
| 作者单位： | 1. 东北农业大学,动物医学院,哈尔滨,150030;沈阳农业大学,畜牧兽医学院,沈阳,110161 2. 沈阳农业大学,畜牧兽医学院,沈阳,110161 3. 东北农业大学,动物医学院,哈尔滨,150030 |
| 基金项目： | 黑龙江省教育厅科学技术研究项目 |
| 摘 要： | 应用反转录多聚酶链式反应(RT-PCR)方法,检测镉中毒的性未成熟鸡卵巢卵泡刺激素受体(FSHR)和黄体生成素受体(LHR)mRNA表达水平的变化.结果表明,对照组二者的表达随时间的延长呈升高趋势,加镉组二者呈不同程度的降低.由此认为,在卵巢发育早期阶段,镉通过降低FSHRmRNA和LHRmRNA的表达水平,影响卵泡刺激素(FSH)和黄体生成素(LH)生理作用的发挥. |
| 关 键 词： | 镉 性未成熟鸡 卵巢 RT-PCR FSHRmRNA LHRmRNA |
| 文章编号： | 0253-468（2008）01-138-04 |
| 收稿时间： | 2006-12-24 |
| 修稿时间： | 2007-05-22 |
The effect of cadmium on the level of FSHRmRNA and LHRmRNA expression in hen ovaries |
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| YANG Shuhua.The effect of cadmium on the level of FSHRmRNA and LHRmRNA expression in hen ovaries[J].Acta Scientiae Circumstantiae,2008,28(1):138-141. | |
| Authors: | YANG Shuhua |
| Institution: | 1. Department of Veterinary Medicine, Northeast Agricultural University, Harbin 150030; 2. Department of Animal Husbandry and Veterinary Medicine, Shenyang Agricultural University, Shenyang 110161 |
| Abstract: | RT-PCR was used to detect the expression level of receptor mRNA of follicle stimulating hormone (FSHR) and luteinizing hormone (LHR) in sexually immature hens. In the control group, the expression level of FSHR and LHR increased with time, but the FSHR and LHR expression decreased in the cadmium-added group. Thus, in the early stage of ovarian growth, cadmium affected the physiological function of FSH and LH by decreasing the mRNA expression level of FSHR and LHR. |
| Keywords: | cadmium sexually immature hen ovaries RT-PCR FSHRmRNA LHRmRNA |
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