| 四氟乙烷（HFC—134a）急性,亚急性毒性的研究 |
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| 引用本文： | 竺乃恺 杜秀英. 四氟乙烷（HFC—134a）急性,亚急性毒性的研究[J]. 环境化学, 1995, 14(1): 66-69 |
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| 作者姓名： | 竺乃恺 杜秀英 |
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| 作者单位： | 中国科学院生态环境研究中心!北京100085 |
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| 摘 要： | 本文研究了四氟乙烷（ＨＦＣ－１３４ａ）和二氟二氯甲烷（ＣＦＣ－１３，氟利昂１２）的急性．亚急性毒性，给大鼠吸入高浓度ＨＦＣ－１３４ａ或ＣＦＣ－１２，观察和记录体重，心电图，血象，生化指标，脏器系数和病理组织学变化，结果显示：实验动物均无病理改变，无死亡，二者的毒性相近，属基本无毒，因此以毒性为指标，ＨＦＣ－１３４ａ可作为ＣＦＣ－１２的替代品。
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| 关 键 词： | 四氟乙烷 氟利昂 急性毒性 亚急性毒性 |
THE STUDY ON THE ACUTE AND SUBACUTE TOXICITY OF TETRAFLUOROETHANE (HFC 134a) |
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| Zhu Naikai Du Xiuying Xia Xijuan. THE STUDY ON THE ACUTE AND SUBACUTE TOXICITY OF TETRAFLUOROETHANE (HFC 134a)[J]. Environmental Chemistry, 1995, 14(1): 66-69 |
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| Authors: | Zhu Naikai Du Xiuying Xia Xijuan |
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| Abstract: | In tnis paper the acute-suoacute toxicities ot HFC-la4a and dicnloroaitiuoro-metnane (CFC-12) were studied using rats. After inhalation of higher concentration of CFC-12 or HFC-134a, the variations of electrocardiogram (ECT), regulational and biochemical parameters of blood, coefficients of internal organs, pathology and histology were measured. The results showed that all things appear to be normal. The toxic effects of HFC-l34a and CFC-12 are similar and both of them are classfied as almost notoxicity. So that HFC-134a could be an alternative to CFC-12 based on the data of the toxicity. |
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| Keywords: | tetrafluoroethane (HFC-134a) dichlorodifluoromethane (CFC-12) acute toxicity subacu te toxicity. |
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