首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Chemical structure and biological activities of lipid A's from various bacterial families
Authors:Otto Lüderitz  Chris Galanos  Volker Lehmann  Hubert Mayer  Ernst Th Rietschel  Jürgen Weckesser
Institution:1. Max-Planck-Institut für Immunbiologie, D-7800, Freiburg/Br.
2. Lehrstuhl für Mikrobiologie der Universit?t, D-7800, Freiburg/Br.
Abstract:The endotoxic principle of lipopolysaccharides (LPS) is localized in their lipid A component. Biological effects of LPS on, for instance, body temperature, blood pressure, and blood picture, are also induced by free lipid A. In contrast to the great variability of the 0-specific chains, the chemical structure of lipid A is much more constant. It is common for Salmonella and similar for other genera of the Enterobacteriaceae. Recently, a number of lipid A's have been recognized that exhibited distinct structural features compared with Enterobacteriaceae. These lipid A's were found to be also distinct with regard to some of their biological properties.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号