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Prenatal diagnosis of cleft lip and/or palate: What do we tell prospective parents?
Authors:Courtney Wilkes  Melissa Graetz  Lilian Downie  Michael Bethune  David Chong
Institution:1. Department of Plastic and Maxillofacial Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia;2. Department of Genetics, Mercy Hospital for Women, Melbourne, Victoria, Australia;3. Department of Medical Imaging and Perinatal Medicine, The Mercy Hospital for Women, Melbourne, Victoria, Australia

Specialist Women's Ultrasound, Melbourne, Victoria, Australia

Abstract:Cleft lip and/or palate (CL/CP) is the most common congenital craniofacial anomaly and parents often ask, “how did this happen?” Patients and families may benefit from access to a multidisciplinary team (MDT) from prenatal diagnosis into early adulthood. Multiple factors can contribute to the development of a cleft. We discuss the epidemiology and risk factors that increase the likelihood of having a newborn with a cleft. The purpose of this article is to review the prenatal investigations involved in the diagnosis and workup of these patients in addition to postpartum treatment, prognostic factors, and counseling families regarding future recurrence risk.
Keywords:
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