The Relationship Between Exposure to Arsenic Concentrations in Drinking Water and the Development of Skin Lesions in Farmers from Inner Mongolia, China |
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Authors: | Linsheng Yang Peter J. Peterson W. Peter Williams Wuyi Wang Shaofan Hou Jian’an Tan |
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Affiliation: | (1) Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Science, Beijing, 100101, P. R. China;(2) MARC, Kings College London, University of London, Franklin-Wilkins Building, 150 Stamford Street London, SE1 9NN, England |
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Abstract: | Associations between the concentration of arsenic naturally occurring in drinking water and the development of skin lesions in people have been documented for some years at various locations around the world. Data on the exposure-response relationship between concentrations of arsenic in drinking water and prevalence of skin lesions in farmers from five locations in Inner Mongolia, China have been collected from the original publications and re-analysed together as a meta-study. The calculated data show a positive linear exposure-response relationship without a threshold. The reasons for this linear correlation are discussed and compared with the data from Xinjiang, another arsenism area located in a different geographical area of China. Here a different relationship was recorded that involved a threshold concentration before skin lesions developed. The significance of these two different exposure-response scenarios is discussed. |
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Keywords: | arsenic concentration arsenism China drinking water exposure-response analysis Inner Mongolia skin lesions |
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