Bioanalytical and instrumental analysis of estrogenic activities in drinking water sources from Yangtze River Delta |
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| Authors: | Xinxin Hu Wei Shi Fu Cao Guanjiu Hu Yingqun Hao Si Wei Xinru Wang Hongxia Yu |
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| Institution: | 1. State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, People’s Republic of China;2. State Environmental Protection Key Laboratory of Monitoring and Analysis for Organic Pollutants in Surface Water, Jiangsu Provincial Environmental Monitoring Center, Nanjing, People’s Republic of China;3. Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, People’s Republic of China |
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| Abstract: | The estrogenic activities of source water from Yangtze River, Huaihe River, Taihu Lake and groundwater in Yangtze River Delta in the dry and wet season were determined by use of reporter gene assays based on African green monkey kidney (CV-1) cell lines. Higher estrogenic activities were observed in the dry season, and the estrogenic potentials in water samples from Taihu Lake were greater than other river basins. None of the samples from groundwater showed estrogen receptor (ER) agonist activity. The 17β-Estradiol (E2) equivalents (EEQs) of water samples in the dry season ranged from 9.41 × 10?1 to 1.20 × 101 ng E2 L?1. In the wet season, EEQs of all the water samples were below the detection limit as 9.00 × 10?1 ng E2 L?1 except for one sample from Huaihe River. The highest contribution of E2 was detected in Yangtze River as 99% of estrogenic activity. Nonylphenol (NP, 100% detection rate) and octylphenol (OP, 100% detection rate) might also be responsible for the estrogenic activities in water sources. Potential health risk induced by the estrogenic chemicals in source water may be posed to the residents through water drinking. |
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