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ADAM12: a novel first-trimester maternal serum marker for Down syndrome
Authors:Jennie Laigaard  Tina Sørensen  Camilla Fröhlich  Bent Nørgaard Pedersen  Michael Christiansen  Kirsten Schiøtt  Niels Uldbjerg  Reidar Albrechtsen  Helle V. Clausen  Bent Ottesen  Ulla M. Wewer
Affiliation:1. Department of Gynecology and Obstetrics, Rigshospitalet, University of Copenhagen, Denmark

Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark

Institute of Molecular Pathology, University of Copenhagen, Copenhagen, Denmark

Department of Gynecology and Obstetrics, Hvidovre University Hospital, Copenhagen, Denmark;2. Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark;3. Institute of Molecular Pathology, University of Copenhagen, Copenhagen, Denmark;4. Department of Gynecology and Obstetrics, Skejby Hospital, Aarhus, Denmark;5. Department of Gynecology and Obstetrics, Hvidovre University Hospital, Copenhagen, Denmark;6. Department of Gynecology and Obstetrics, Rigshospitalet, University of Copenhagen, Denmark

Department of Gynecology and Obstetrics, Hvidovre University Hospital, Copenhagen, Denmark

Abstract:
Keywords:ADAM12  prenatal diagnosis  Down syndrome  IGFBP-3 protease  IGFBP-5 protease  PAPP-A
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