首页 | 本学科首页   官方微博 | 高级检索  
     检索      

新装修居室环境中甲醛的遗传毒性
引用本文:仇小强,庞伟毅,何凤英,韦 娟,段 鹏,张志勇,韦小敏.新装修居室环境中甲醛的遗传毒性[J].环境科学研究,2009,22(5):584-588.
作者姓名:仇小强  庞伟毅  何凤英  韦 娟  段 鹏  张志勇  韦小敏
作者单位:广西医科大学公共卫生学院,广西 南宁 530021
基金项目:广西科学研究与技术开发计划项目 
摘    要:通过环境卫生学调查和遗传毒性试验,了解甲醛对人体健康的危害性. 经随机抽样选择南宁市新装修的130户居室进行ρ(甲醛)测定,并对其中甲醛超标最严重的25户家庭成员共59人进行健康问卷调查;用单细胞凝胶电泳(彗星试验)方法和微核试验方法检测甲醛对体外培养人体淋巴细胞的遗传损伤作用. 结果表明:在南宁市130户新装修的居室环境中,甲醛超标率达73.1%,甲醛超标组居民的呼吸道和神经系统不良反应发生率升高,随着入住时间的延长,ρ(甲醛)下降,不良反应发生率也下降. 体外培养人体淋巴细胞试验结果显示:与对照组相比,甲醛低、中和高剂量组的彗星细胞发生率分别增加39.2%,80.6%和46.0%,彗星细胞尾长度增加23.9,40.6和28.3 μm,微核率增加218.6%,565.0%和647.0%;甲醛超标会使居住人群出现呼吸系统和神经系统疾病,随着时间的推移,室内ρ(甲醛)降低,对人体健康影响程度减少;甲醛可致体外培养人淋体巴细胞的遗传损伤. 

关 键 词:甲醛    污染    遗传毒性
收稿时间:2008/9/19 0:00:00
修稿时间:2008/12/1 0:00:00

Study on Formaldehyde Heredity Toxicity in Indoor Environments of Recently Renovated Houses
QIU Xiao-qiang,PANG Wei-yi,HE Feng-ying,WEI Juan,DUAN Peng,ZHANG Zhi-yong and WEI Xiao-min.Study on Formaldehyde Heredity Toxicity in Indoor Environments of Recently Renovated Houses[J].Research of Environmental Sciences,2009,22(5):584-588.
Authors:QIU Xiao-qiang  PANG Wei-yi  HE Feng-ying  WEI Juan  DUAN Peng  ZHANG Zhi-yong and WEI Xiao-min
Institution:School of Public Health, Guangxi Medical University, Nanning 530021, China
Abstract:The goal of this study was to use environmental health surveys and heredity toxicity analysis to understand the effects of indoor environmental formaldehyde pollution on habitants' health.130 houses in Nanning City renovated in the last three years were selected as research objects by randomized sampling method.25 high formaldehyde-level houses were selected for trace surveys,which included indoor environmental pollution and habitants' health.Human lymphatic cells were divided into four groups including neg...
Keywords:formaldehyde  pollution  heredity toxicity  
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《环境科学研究》浏览原始摘要信息
点击此处可从《环境科学研究》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号