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Promotion of hexadecyltrimethyleamine bromide to the damage of Alexandrium sp. LC3 by cupric glutamate |
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| Authors: | LI Hao MIAO Jin-lai CUI Feng-xia and LI Guang-you |
| Institution: | 1. Key Laboratory of Marine Biological Active Substances, SOA, Qingdao 266061, China;Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China 2. Key Laboratory of Marine Biological Active Substances, SOA, Qingdao 266061, China 3. College of Food Science and Technology, Ocean University of China, Qingdao 266003, China |
| Abstract: | The effect of hexadecyltrimethyleamine bromide (HDTMAB) on the removal of Alexandrium sp. LC3 under cupric glutamate stress was investigated. Toxic effect of cupric glutamate on Alexandrium sp. LC3 was significantly promoted in the presence of HDTMAB, especially at 3.0 cmc of HDTMAB. It was found that the sulfhydryl group content of the cell decreased, while the malonaldehyde content and membrane permeability increased when Alexandrium sp. LC3 was treated with HDTMAB and cupric glutamate complex, compared with cupric glutamate alone. The data suggest that HDTMAB might stimulate the damage of Alexandrium sp. LC3 by enhancing the membrane permeability. |
| Keywords: | HDTMAB cupric glutamate A lexandrium sp LC3 cell membrane permeability |
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