Regulation of hepatocyte proliferation |
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Authors: | G Ruhenstroth-Bauer M Goldberg S Vogl |
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Institution: | 1. Max-Planck-Institut für Biochemie, D-8033, Martinsried
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Abstract: | After partial hepatectomy the low proliferation rate of hepatocytes increases dramatically. This is based on a feed-back system whose central link is a liver cell proliferation hormon, the so-called hepatopoietin. The hormon originates from the Peyer's patches: after their resection, the liver cell proliferation after partial hepatectomy decreases by about 80%. Hepatopoietin effects organ specific but species nonspecific. |
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