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The association between ‘faint-positive’ amniotic fluid acetylcholinesterase and fetal malformations |
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| Authors: | Yoel Sadovsky MD Michelle L Robbin Barbara F Crandall Roy A Filly Mitchell S Golbus |
| Institution: | 1. Department of Obstetrics and Gynecology and Reproductive Sciences and Department of Radiology, University of California, San Francisco, San Francisco, California, U.S.A.;2. Department of Psychiatry and Pediatrics, University of California, Los Angeles, California, U.S.A. |
| Abstract: | The finding of a ‘faint-positive’ acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out significant fetal malformations. |
| Keywords: | ‘Faint-positive’ acetylcholinesterase Amniocentesis Gastroschisis |