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Risk factors associated with transcervical CVS losses
Authors:Dr Mitchell S Golbus  Joe Leigh Simpson  Sarah E Fowler  Felix de la Cruz  Robert J Desnick  Ronald Wapner  David H Ledbetter  Herbert Lubs  Maurice J Mahoney  Eugene Pergament  George G Rhoads  Joseph D Schulman  Julia Zachary
Institution:1. University of Tennessee, Memphis;2. Memphis, TC;3. George Washington University, Washingion, DC

Henry Ford Hospital, Southfield, MI;4. National Institute of Child Health and Development, Bethesda, MD;5. Mount Sinai School of Medicine, New York, NY;6. Jefferson School of Medicine, Philadelphia, PA;7. Baylor College of Medicine, Houston, TX;8. University of Miami, Miami, FL;9. Yale University, New Haven, CT;10. Northwestern University Medical School, Chicago, IL;11. Robert Wood Johnson School of Medicine, New Brunswick, NJ;12. Genetics and IVF Institute, Fairfax, VA, U.S.A.

Abstract:Factors found to be associated with pregnancy loss after transcervical CVS were race (higher for non-white), history of spontaneous abortion, unplanned pregnancy, history of spotting or bleeding during the pregnancy prior to CVS, and placental position (higher for fundal or lateral locations). Whether the increase in loss risk is due to the factor, per se, or the factor plus the CVS cannot be determined due to the lack of appropriate control data.
Keywords:Prenatal diagnosis  Chorionic villus sampling  Risk factors  Spontaneous abortion
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