Chromosomal abnormalities associated with a single umbilical artery |
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Authors: | Dr T Y Khong K George |
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Institution: | Departments of Obstetrics and Gynaecology, Queen Victoria Hospital, Adelaide Medical Centre for Women and Children, Australia |
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Abstract: | A single umbilical artery was seen in 10 out of 117 cytogenetically abnormal pregnancies. The abnormal karyotypes found to be associated with a single umbilical artery were trisomy 18 (n = 5), monosomy X (n = 2), triploidy (n = 1), sex chromosome (47,XYY; n = 1) and translocation (46t(X,5)(q13p15); n = 1). With the exception of the translocation case, all cases with a single umbilical artery had anatomical defects which were detectable ultrasonographically. This suggests that a single umbilical artery alone is not an indication for prenatal fetal karyotyping. |
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Keywords: | Single umbilical artery Fetal karyotype Prenatal diagnosis |
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