The significance of choroid plexus cysts in fetuses at 18–20 weeks. An indication for amniocentesis? |
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| Authors: | Richard J Howard Susan M Tuck Joanne Long Valerie A Thomas |
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| Institution: | Department of Obstetrics and Gynaecology, and Department of Histopathology, The Royal Free Hospital and School of Medicine, Pond Street, London NW3, U.K. |
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| Abstract: | Over a period of 25 months, all antenatal patients were offered a detailed ultrasound scan at 18–20 weeks' gestation. The lateral cerebral ventricles were scanned for the presence of choroid plexus cysts. Fifty-one patients found to have choroid plexus cysts were offered amniocentesis to exclude chromosomal abnormalities. One pregnancy, in which the only abnormality found was bilateral choroid plexus cysts, was terminated after trisomy 18 was detected on amniocentesis at 19 weeks. The other 50 pregnancies had normal fetal outcomes. The significance of the isolated finding of choroid plexus cysts is reviewed. |
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| Keywords: | Choroid plexus cysts Trisomy 18 |
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