Prognosis of fetuses with a cystic hygroma |
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| Authors: | Harold S Bernstein Roy A Filly James D Goldberg Dr Mitchell S Golbus |
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| Institution: | Departments of Obstetrics, Gynecology and Reproductive Sciences, and of Radiology, University of California, San Francisco, U.S.A. |
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| Abstract: | This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non-immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two-thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non-septated lesions which resolved in utero. |
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| Keywords: | Cystic hygroma Fetal aneuploidy Septation Non-immune hydrops |
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