A rare case of a false-negative finding in both direct and culture of a chorionic villus sample |
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| Authors: | Lesley Pindar Melanie Whitehouse Kevin Ocraft |
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| Institution: | Department of Cytogenetics, City Hospital, Hucknall Road, Nottingham NG5 IBP, U.K. |
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| Abstract: | A discrepancy is reported between the karyotype of both direct and cultured chorionic villus cells (46,XX) and a fetal skin biopsy (47,XX,+18). The significance of this result is discussed and compared with similar discordant findings reported in the literature. |
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| Keywords: | False-negative CVS diagnosis Trisorny 18 |
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