Rapid karyotyping in ectopic pregnancies |
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| Authors: | Daniel Cohen MD Irma Bragos Cesar Berta Mónica Fodor Eduardo Alonso César Nasio Liliana Kreiman Rafael Pineda |
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| Affiliation: | 1. Departamento de Genética Humana, Sanatorio de la Mujer, Rosario, Argentina;2. Servicio de Ginecología y de, Argentina;3. Anatomia Patológica, Hospital de Emergencias Dr Clemente Alvarez, Rosario, Argentina |
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| Abstract: | The aim of this study was to determine the feasibility of karyotyping ectopic Fallopian tube pregnancies utilizing dividing cytotrophoblast cells. Villi from 78 ectopic conceptuses were processed by the direct chromosome technique and cytogenetic diagnosis was successful in 60 cases (76-9 per cent). The amount of villi obtained, as well as villus morphology, was correlated with cytogenetic success rate. Histological examination of the Fallopian tube was also carried out. A total of 47 cases were chromosomally abnormal (78-3 per cent), which is the highest frequency of cytogenetic abnormalities reported to date. |
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| Keywords: | Ectopic Fallopian tube pregnancy Cytogenetic diagnosis Direct chromosome preparation |
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