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Maternal serum free β-human chorionic gonadotrophin levels in twin pregnancies: Implications for screening for down's syndrome
Authors:N J Wald  J W Densem
Institution:Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew's Hospital Medical College, Charterhouse Square, London EC1M 6BQ, U.K.
Abstract:Free β-human chorionic gonadotrophin values are, on average, 1·90 times greater in twin pregnancies than in singleton pregnancies 95 per cent confidence interval (CI) 1·69–2·13]. This information can be used in screening for Down's syndrome, so that twin pregnancies can be interpreted in addition to singleton pregnancies.
Keywords:Down's syndrome  screening  twin pregnancies  free β-human chorionic gonadotrophin
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