Maternal serum free β-human chorionic gonadotrophin levels in twin pregnancies: Implications for screening for down's syndrome |
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Authors: | N. J. Wald J. W. Densem |
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Affiliation: | Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew's Hospital Medical College, Charterhouse Square, London EC1M 6BQ, U.K. |
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Abstract: | Free β-human chorionic gonadotrophin values are, on average, 1·90 times greater in twin pregnancies than in singleton pregnancies [95 per cent confidence interval (CI) 1·69–2·13]. This information can be used in screening for Down's syndrome, so that twin pregnancies can be interpreted in addition to singleton pregnancies. |
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Keywords: | Down's syndrome screening twin pregnancies free β-human chorionic gonadotrophin |
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