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Amniotic fluid alpha-fetoprotein and acetylcholinesterase measurements in pregnancies associated with gastroschisis
Authors:Christina Goldfine PhD  James E Haddow  George J Knight  Glenn E Palomaki
Institution:Foundation for Blood Research, Scarborough, ME04074, U.S.A.
Abstract:In this study we define for the first time the distribution of alpha-fetoprotein levels and acetylcholinesterase ratios in amniotic fluid samples associated with fetal gastroschisis. Elevated alpha-fetoprotein levels and positive acetylcholinesterase measurements are found in virtually all cases, indicating that these combined measurements are highly reliable in detecting this lesion.
Keywords:Gastroschisis  Amniotic fluid  Alpha-fetoprotein  Acetylcholinesterase
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