| Identification of 1-hydroxypyrene in urine of dogs after pyrene injection and its excretion |
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| 作者姓名： | Zhao Zhenhu Quan Wenyi |
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| 作者单位： | Zhao Zhenhua and Quan WenyiBeijing Municipal Research Institute of Environmental Protetion，Beijing 100037，China |
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| 基金项目： | This project is funded by the National Natural Sciences Foundation of China, and partially supported by Beijing Municiple Environmental Protection Bureau. |
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| 摘 要： | With high performance liquid chromatograph and fluorospectrometry, 1-hydroxypyrene is identified as a metabolite of pyrene in the urine of dogs after intramuscular injection of pyrene. When three successive doses of 1,2 and 5 μmol/kg wt. pyrene administered, urinary excretion of 1-hydroxypyrene reaches the peak level between 24th and 48th hours. Excreted 1-hydroxypyrene consists of only about 0.05% of injected pyrene.
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| 关 键 词： | 1-hydroxypyrene pyrene polynuclear aromatic hydrocarbons. |
| 收稿时间： | 1990/7/11 0:00:00 |
Identification of 1-hydroxypyrene in urine of dogs after pyrene injection and its excretion |
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| Zhao Zhenhu,Quan Wenyi.Identification of 1-hydroxypyrene in urine of dogs after pyrene injection and its excretion[J].Journal of Environmental Sciences,1991,3(2):27-132. |
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| Authors: | Zhao Zhenhua and Quan WenyiBeijing Municipal Research Institute of Environmental Protetion Beijing China |
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| Institution: | Zhao Zhenhua and Quan WenyiBeijing Municipal Research Institute of Environmental Protetion,Beijing 100037,China |
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| Abstract: | |
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| Keywords: | 1-hydroxypyrene pyrene polynuclear aromatic hydrocarbons |
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