Influence of 1,2,4,5-tetrazine derivatives on growth of bacterial consortium isolated from soil |
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Authors: | Andrzej Borkowski Mateusz Szala Dorota Wolicka |
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Affiliation: | 1. Department of Environmental Protection and Natural Resources , University of Warsaw , Warsaw, Poland andrzejborkowski2@gmail.com;3. Military University of Technology , Warsaw, Poland;4. Department of Geochemistry, Mineralogy and Petrology , University of Warsaw , Warsaw, Poland |
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Abstract: | This article presents the results of laboratory studies of the influence of tetrazine derivatives on the growth kinetic parameters of soil bacteria. 3,6-Dihydrazinotetrazine (DHTz), 3,6- bis(3,5-dimethylpyrazol-1-yl)-dihydro-1,2,4,5-tetrazine (DMPDHT) and N,N′-bis(1,2,4,5-tetrazine-6-(3,5-dimethylpirazylo))hydrazine (BDMPT) were applied. 3,6-Dihydrazinetetrazine had the largest influence on the growth of bacteria, reflected in a significant lengthening of the lag-phase and a decrease in the specific growth rate. Dehydrogenase activity was also determined in bacterial cultures exposed to tetrazine derivatives. Dehydrogenases remained active even at DHTz concentrations of 80 mg · L?1, which completely inhibited bacterial growth. The compounds studied variously influence the kinetics of growth in the bacterial consortium; at the same time, they undergo biodegradation in soil by autochthonous microflora. |
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Keywords: | tetrazines high-energy materials bacterial activity |
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