Spectroscopic studies and biological evaluation of some transition metal complexes of a novel Schiff base ligands derived from 5-arylazo-salicyladehyde and o-amino phenol |
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| Authors: | Moamen S. Refat Ibrahim M. El-Deen Ragab R. Amin Samir El-Ghol |
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| Affiliation: | 1. Department of Chemistry , Faculty of Science-Port Said, Suez Canal University , Port Said, Egypt;2. Department of Chemistry , Faculty of Science-Taif, Taif University , Taif 888, Kingdom Saudi Arabia msrefat@yahoo.com;4. Department of Chemistry , Faculty of Science-Port Said, Suez Canal University , Port Said, Egypt;5. Department of Chemistry , Faculty of Science-Taif, Taif University , Taif 888, Kingdom Saudi Arabia |
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| Abstract: | Synthesis and characterization of Cu(II), Ni(II), and Zn(II) Schiff bases complexes resulted from the condensation of salicylaldehyde derivatives with o-amino phenol were discussed using elemental analysis (carbon, hydrogen, and nitrogen), molar conductance, magnetic measurements, mass spectra, and electronic spectra. The essential bands of infrared, 1HNMR, and UV-Vis spectra as well as thermogravimetric analysis corresponding to the active groups within the three ligands and their complexes were interpreted. The dehydration and decomposition processes of the [Cu(H2L1)(H2O)](OAc)2, [Ni(H2L1)(H2O)]SO4 · H2O, [Zn(H2L1)(H2O)]SO4 · H2O, [Cu(H2L2)(H2O)](OAc)2, [Ni(H2L2)(H2O)]SO4 · H2O, [Zn(H2L2)(H2O)]SO4 · 2H2O, [Cu(H2L3)(H2O)](OAc)2 · H2O, [Ni(H2L3)(H2O)]SO4 · 2H2O, [Zn(H2L3)(H2O)]SO4 complexes were studied thermodynamically using the integral method applying the Coats–Redfern and Horowitz–Metzger equations and the thermodynamic parameters were calculated. It was found from the elemental analysis and the thermal studies, that the ligand behaves as tridentate ligand forming chelates with 1 : 1 (metal : ligand) stoichiometrically. The molar conductance measurements of the complexes in dimethyl sulfoxide solvent indicate that the complexes have an electrolytic nature. The biological activities of the three ligands in comparison with metal(II) complexes were studied against different Gram positive and Gram negative bacteria. |
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| Keywords: | spectroscopic studies biological evaluation transition metal Schiff base 5-arylazo-salicyladehyde o-amino phenol |
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