Rapid liquid chromatographic analysis of Metoclopramide in pharmaceutical preparations |
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| Authors: | Hassan Y Aboul‐Enein M Rafiqul Islam |
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| Institution: | Drug Development Laboratory, Radionuclide and Cyclotron Operations Department , King Faisal Specialist Hospital and Research Centre , P.O. Box 3354, Riyadh, 11211, Kingdom of Saudi Arabia |
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| Abstract: | A sensitive, accurate and reproducible method for the analysis of metoclopramide, a gastrointestinal drug, has been described. An isocratic HPLC elution method was employed which requires about 10 minutes to be performed. The concentration of metoclopramide hydrochloride preparations was found to be 95.1 ±0.3% and 94.21 ±0.25% in tablet and injection formulations, respectively. |
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| Keywords: | High performance liquid chromatography (HPLC) determination metoclopramide pharmaceutical formulations |
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