|
|||||
|
|
Transthyretin (prealbumin) binding of PCBS, a model for the mechanism of interference with vitamin A and thyroid hormone metabolism |
|
| Authors: | A Brouwer KJ van den Berg WS Blaner DewS Goodman |
| Institution: | Radiobiological Institute TNO, 151 Lange Kleiweg, 2280 HV, Rijswijk, The Netherlands Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, U.S.A. |
| Abstract: | In this study a direct interaction of a metabolite of 3,4,3′,4′-tetrachlorobiphenyl with transthyretin (prealbumin) was observed, leading to reduced plasma levels of retinol, RBP and thyroxin in rats and mice. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |