The 5 principles of “Design for Safer Nanotechnology” |
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| Authors: | Gregory Morose |
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| Institution: | 1. Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA;2. Dept. of Biological Engineering, MIT, Cambridge, MA, USA;3. Dept. of Materials Science & Engineering, MIT, Cambridge, MA, USA;4. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA;5. Howard Hughes Medical Institute, Chevy Chase, MD, USA;6. Dept. of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, RI, USA;1. Institute of Occupational Medicine (IOM), Research Avenue North, Edinburgh, UK;2. Avanzare Innovación Tecnológica S.L., Av. Lentiscares, 4-6, 26370 Navarrete, La Rioja, Spain;3. GAIKER Technology Centre, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, E-48170 Zamudio, Spain;4. National Research Centre for the Working Environment (NRCWE), Lersoe Park Alle 105, 2100 Copenhagen, Denmark;5. TEMAS AG, 8048 Zurich, Switzerland;6. Institut national de l''environnement industriel et des risques (INERIS), Verneuil-en-Halatte 60550, France;7. Swiss Federal Laboratories for Materials Science and Technology (Empa), Technology and Society Lab (TSL), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland;8. Roumen Tsanev Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria;9. Nanomakers, 1 Rue de Clairefontaine, 78 120 Rambouillet, France;10. Nanotechnology Industries Association (NIA), Avenue Tervueren 143, 1150 Brussels, Belgium;11. TNO, Princetonlaan 6, 3584 CB Utrecht, Netherlands;12. School of Health Sciences, The University of Manchester, Oxford Rd., Manchester M13 9PL,UK;1. INM-Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany;2. National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands;3. Innovation Center INM-Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany |
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| Abstract: | Nanoparticles have been incorporated in hundreds of different types of products, and the novel properties of nanomaterials offer great promise to provide new technological breakthroughs. However, nanotechnology is an emerging technology which has potential health and safety risks throughout its product life cycle. The health risk of a nanoparticle is a function of both its hazard to human health and its exposure potential. It is prudent for companies to try to mitigate the potential risks of nanoparticles during the design stage rather than downstream during manufacturing or customer use. The intent of this paper is to propose five design principles for product designers to use during the design stage for products that contain nanoparticles. By using these design principles, the health risk of the nanoparticle may be mitigated by potentially lowering the hazard and/or the exposure potential of the nanoparticle. These proposed design principles are largely untested and are offered as an initial framework that will require more testing, validation, and refinement. |
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