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Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in breast milk of first-time Irish mothers: impact of the 2008 dioxin incident in Ireland |
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| Authors: | Pratt Iona S Anderson Wayne A Crowley Dominique Daly Sean F Evans Rhodri I Fernandes Alwyn R Fitzgerald Margaret Geary Michael P Keane Declan P Malisch Rainer McBride John Morrison John J Reilly Alan Tlustos Christina |
| Institution: | a Food Science and Standards Division, Food Safety Authority of Ireland, Lower Abbey Street, Dublin 1, Ireland b Public Health Medicine, HSE East, Dublin, Ireland c Coombe Women’s Hospital, Dublin 8, Ireland d Food and Environment Research Agency (FERA), York, UK e Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland f Department of Obstetrics, National Maternity Hospital, Dublin, Ireland g State Institute for Chemical and Veterinary Analysis of Food, Bissierstrasse 5, Freiburg, Germany1 h The State Laboratory, Backweston Campus, Co. Kildare, Ireland i Department of Obstetrics and Gynaecology, University College Hospital Galway, Galway, Ireland |
| Abstract: | The 2008 dioxin incident in Ireland resulted in elevated concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in Irish pork and pork products, due to the consumption of contaminated animal feed by pigs. In order to investigate any resulting impact on the Irish population, these contaminants were measured in pooled breast milk samples from 109 first-time mothers, collected in 2010. A comparison of the results with similar data from 2002 revealed generally lower concentrations of PCDD/Fs and dioxin-like PCBs in the 2010 samples, confirming the declining trend reported by many authors. Contaminant concentration levels for both 2002 and 2010 were generally slightly lower than those reported internationally, with a mean combined PCDD/F and PCB WHO-TEQ of 9.66 pg g−1 fat, for an overall pooled sample of milk from 2010. An apparent slight increase in PCDFs was observed between 2002 and 2010 (from 2.73 pg WHO-TEQ g−1 fat to 3.21 pg WHO-TEQ g−1 fat), with the main contributory congener being 2,3,4,7,8-PentaCDF. While it cannot be totally discounted that the slight increase in 2,3,4,7,8-PentaCDF and in the overall PCDF WHO-TEQ in breast milk could be attributable to consumption of Irish pork during the 2008 incident, we consider that it is more likely that this was due to other factors, including the predominantly urban/industrial sampling locations for the 2010 samples, compared to 2002. |
| Keywords: | Human milk PCDD/Fs PCBs Irish dioxin incident |
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