空气氟化物污染对工人淋巴细胞微核的诱发

对某磷肥厂慢性接触空气氟化物污染的４０ 名工人外周血淋巴细胞的微核发生频率进行了分析研究．结果表明：接触氟化物污染工人的外周血淋巴细胞的微核发生率和微核细胞率均显著高于ＣＫ．人体对低浓度化学污染物的损害作用可产生适应机制，这种适应机制的形成需１０ ａ 左右．吸烟能加剧氟对微核的诱发作用．

OBSERVATION OF MICRONUCLEI IN LYMPHOCYTES OF WORKERS EXPOSED TO FLUORIDE

The frequencies of micronuclei (MN) in peripheral blood lymphocytes of 40 workers chronically exposed to fluoride at a phosphate fertilizer factory were studied. It showed that both the mean MN frequency and the frequency of cells with MN in lymphocytes of the workers exposed to fluoride were much higher than CK. MN frequencies of the workers increased in fluoride exposure period within 10 a and MN/cell value began to decrease after fluoride exposure for about 10 a. An adaptive mechanism to chemical pollution at low concentration, which could protect genetic material from chemical damage, would be produced in human body exposed to the chemicals for about 10 a. Smoking could enhance induction effect of fluoride on MN in lymphocytes of workers.