Effects of perfluorooctane sulfonate on behavioural activity,regeneration and antioxidant enzymes in planarian Dugesia japonica |
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Authors: | Zuoqing Yuan Wang Meng Yan Zhou |
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Institution: | School of Life Sciences, Shandong University of Technology, 12 Zhangzhou Road, Zibo 255049, PR China |
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Abstract: | Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant and has been found to be the predominant perfluorinated chemicals (PFCs) in the environment. In the present study, planarian Dugesia japonica is employed to investigate the toxicity of this compound. The behavioural activity, survival, regeneration and antioxidant enzyme activities of the D. japonica exposed to PFOS were investigated. The results showed that the planarian D. japonica is very sensitive to low concentration pollutants including PFOS and suitable for toxicological bioassays. PFOS has severe toxicity in inducing oxidative stress, regeneration and development toxicity in planarians. The toxicity is indicated by reduced planarian locomotor velocity (pLMV), reduced appearance of auricles in regenerating animals, changed in antioxidant enzyme SOD and CAT activities. The information presented in this study will help elucidating the PFOS-induced toxicity in aquatic organisms. |
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Keywords: | antioxidant enzyme activities perfluorooctane sulfonate planarian regeneration toxicity |
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