Generator column determination of aqueous solubilities for non-ortho and mono-ortho substituted polychlorinated biphenyls

Aqueous solubilities of four non-ortho and eight mono-ortho substituted PCBs were determined using a generator-column technique followed by subsequent off-line GC/ECD analysis of the aqueous solutions. The method is based on pumping water through a column containing glass beads coated with the congener being studied and has been used to measure solubilities at room temperature. The method circumvents many of the experimental difficulties encountered with the traditional shake-flask system. Aqueous solubility of 3,3′,4,4′-tetrachlorobiphenyl determined by this procedure is compared with data obtained from the shake-flask method and the computational method. The precision of replicate measurements is better than ±6.5%. Aqueous solubilities determined for 12 congeners ranged from 6.07 × 10⁻¹¹ to 4.47 × ⁻⁹ mol/L and generally decreased with molecular weight and increased with degree of ortho-chlorine substitution within a molecular-weight class.