Assessment of locomotion behavioral defects induced by acute toxicity from
heavy metal exposure in nematode Caenorhabditis elegans |
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Authors: | WANG Dayong and XING Xiaojuan |
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Institution: | Key Laboratory of Developmental Genes and Human Disease, Ministry of Education, Southeast University Medical School, Nanjing 210009, China;Department of Genetics and Developmental Biology, Southeast University, Nanjing 210009, China |
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Abstract: | Locomotion behaviors are susceptible to disruption by a broad spectrum of chemicals and environmental stresses. However, no systematic testing of locomotion behavior defects induced by metal exposure has been conducted in the model organism of nematode Caenorhabditis elegans. In this study, the acute toxicity from heavy metal exposure on the locomotion behaviors was analyzed in nematodes. Endpoints of head thrash, body bend, forward turn, backward turn, and Omega/U turn were chosen to evaluate the locomotio... |
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Keywords: | locomotion behavior heavy metal acute exposure C elegans |
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