四环素类抗生素环境行为及其生态毒性研究进展

四环素类抗生素(TCs)是目前世界上应用最广泛的抗生素种类之一,由于该类化合物不易被生物体吸收,难以在环境中降解,且在常规的污水处理系统中难以彻底去除,对生态系统和人类健康造成严重威胁。梳理分析了环境中TCs的来源及污染现状,详细阐述了其在环境中的迁移转化和降解,并对其引起的生态毒性效应进行了总结,指出了该类污染物的生态风险;对未来的研究进行了展望,提出TCs的环境行为应从环境多介质层面进行分析,同时加强对TCs生态毒性机理及其与其他环境污染物的联合毒性效应的研究。

Research progress on environmental behaviors and ecotoxicity of tetracycline antibiotics

Tetracycline antibiotics (TCs) are among the most widely used antibiotics in the world. They are hardly absorbable by organisms, and resistant to biodegradation in the environment, thus being difficult to remove in conventional wastewater treatment systems, and posing serious threats to ecosystems and human health. The sources and pollution occurrence of TCs in the environment were reviewed, their transfer, transformation and degradation were described, and their ecological and bio-toxic effects were summarized. Finally, the ecological risks of these pollutants and the prospects of future research were proposed. It was suggested that the environmental behaviors of TCs should be assessed at the multi-media environmental levels. More studies should be conducted on their ecotoxic mechanisms and their joint toxic effects with other environmental pollutants.