The reaction of nitrogen dioxide with lung surface components: The reaction with cholesterol |
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Authors: | Takahiro Kobayashi Kentaro Kubota |
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Affiliation: | Division of Basic Medical Sciences, The National Institute for Environmental Studies Yatabe, Ibaraki, 305, Japan |
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Abstract: | The reaction of nitrogen dioxide (NO2) with cholesterol was investigated. NO2 reacted with the hydroxyl group in cholesterol to produce cholesteryl nitrite. In this reaction, other minor products were observed. Cholesteryl nitrate, however, was not detected as was reported by other workers. Water accelerates and oxygen retards this reaction. |
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