| 含铅,无铅汽油车尾气排出物遗传毒性比较 |
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| 引用本文： | 袁东 叶舜华. 含铅,无铅汽油车尾气排出物遗传毒性比较[J]. 上海环境科学, 1999, 18(7): 328-330,327 |
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| 作者姓名： | 袁东 叶舜华 |
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| 作者单位： | 上海医科大学，上海医科大学，上海医科大学 上海 200032，上海 200032，上海 200032 |
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| 基金项目： | 国家自然科学基金 编号 39670623 |
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| 摘 要： | 利用台架试验模拟汽车行驶工况，收集了发动机使用无铅汽油，含铅汽油燃烧后的尾气颗粒物，对其中吸附的有机物进行了提取，并以Ａｍｅｓ试验，中国仓鼠肺细胞体外微核实验等方法，从基因，染色体水平检测了两种颗粒提取的遗传毒性。
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| 关 键 词： | 汽车尾气 含铅汽油 无铅泊油 Ames试验 遗传毒性 |
Comparison on Genotoxiocity of Two Vehicle Exhausts Using Leaded and Unleaded Gasoline |
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| Yuan Dong Ye Shunhua Zhou Wei. Comparison on Genotoxiocity of Two Vehicle Exhausts Using Leaded and Unleaded Gasoline[J]. Shanghai Environmental Science, 1999, 18(7): 328-330,327 |
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| Authors: | Yuan Dong Ye Shunhua Zhou Wei |
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| Abstract: | Two kinds of gasoline (leaded and unleaded) have been tested on Engine Dynamometer, the total paniculate matter of exhausts were collected, and from which the organic substances were extracted. By using Ames test and micronucleus assay in CHL cells, genotoxicity of two kinds of extracted organic substances were determined from the end points of gene and chromosome, the results showed that unleaded gasoline has the potential of reducing emission of particles, but both kinds of extract could increase the number of histidine-independent colonies in salmonells/ microsomal test and induce micronuclei in CHL cells, and also dose-response relationship were found. As the same particles were being tested, there were no significant differences in genotoxicity between two kinds of extracts. |
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| Keywords: | Vehicle exhaust Leaded gasoline Unleaded gasoline Ames test Micronucleus assay Genotoxicity |
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