Cytotoxicity of lambda-cyhalothrin on the macrophage cell line RAW264.7 |
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Authors: | Quan Zhang Cui Wang Liwei Sun Ling Li Meirong Zhao |
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Affiliation: | Research Center of Environmental Science,College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou 310032,China |
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Abstract: | The wide use and wide-spectrum toxicity of synthetic pyrethroids (SPs) insecticides make them an emerging ecotoxicological concern. Some previous studies showed that SPs possessed cytotoxicity in some immune cells such as human lymphocytes and rat bone marrow. However, the cytotoxicity of SPs to macrophages, which are crucial to innate immunity, has not been explored. In the present report, we investigated a new pyrethroid insecticide, lambda-cyhalothrin (LCT), which may increase the generation of reactive ... |
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Keywords: | lambda-cyhalothrin macrophage reactive oxygen species cytotoxicity |
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