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THE CASE FOR DIRECT MEASUREMENT OF ENVIRONMENTAL RESPONSE TO HAZARDOUS MATERIALS1
Authors:John Cairns
Abstract:ABSTRACT: Direct measurement of response thresholds of complex biological systems to toxic chemicals is now possible using microcosms and other simulation techniques. Extrapolation to no-observable response using application factors and data from single species toxicity tests is less precise than direct measurements.
Keywords:ecotoxicology  hazardous materials  regulatory criteria  toxicity testing  application factors  aquatic toxicology
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