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Pharmacokinetics of 2,3,7,8-TCDD in man
Authors:H Poiger  C Schlatter
Institution:

Institute of Toxicology, Federal Institute of Technology and University of Zurich, CH-8603, Schwerzenbach, Switzerland

Abstract:A single dose of 1.14 ng of 3H-2,3,7,8-TCDD/kg bw, ingested by a human volunteer, was absorbed almost completely from the intestine (> 87 %). The resulting adipose tissue levels, measured 13 and 69 days after dosage were 3.09±0.05 and 2.85±0.28 ppt, respectively. The dioxin was cleared from the body with a half life of elimination of 2120 days.
Keywords:
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