植物细胞色素P450酶系的研究进展及其与外来物质的关系

植物细胞色素P45 0是分子量为 40— 60KD、结构类似的一类血红素 硫铁蛋白。它以可溶性和膜结合两种形态存在于植物细胞内 ,可催化多种化学反应 ,在防御植物免受有害物质侵害方面具有重要作用。目前已克隆 90多个植物细胞色素P45 0基因。本文概述了植物P45 0基因表达调控与环境、发育、组织特异性关系的研究进展。认为植物P45 0同工酶在环境毒物生物修复和在抗外源毒素的转基因植物方面具有很高的应用前景

The research progress of plant cytochrome P450 enzymes and their relationship with xenobiotics

Plant cytochromes P450 enzymes are a diverse array of heme thiolate proteins with similar structure in the range of molecular weight 40 to 60KD. They are found in various subcellular locations in soluble and membrane bound forms and play an important role in preventing the plants from injury of harmful substances by catalyzing many kinds of reaction. At present, more than 90 genes for cytochromes P450 in plants are cloned. The research progress of expression of plant P450 gene family is discussed in relation to regulation in response to environmental and developmental cues and tissue location. It is thought that the application prospectives for the bioremediation of environmental toxicants by plant P450 isozymes and for expressing these P450s in transgenic plants with anti exotoxicants are high.