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| 上海地区肉类和鱼类食品中多氯联苯含量特征及其对人体的生物有效性 | |
| 引用本文： | 韩姝媛,余应新,李俊岭,王德庆,吴明红,盛国英,傅家谟.上海地区肉类和鱼类食品中多氯联苯含量特征及其对人体的生物有效性[J].环境科学学报,2010,30(6):1322-1330. |
| 作者姓名： | 韩姝媛 余应新 李俊岭 王德庆 吴明红 盛国英 傅家谟 |
| 作者单位： | 1. 上海大学环境与化学工程学院环境污染与健康研究所,上海,200444 2. 上海大学环境与化学工程学院上海射线应用研究所,上海,200444 3. 上海大学环境与化学工程学院环境污染与健康研究所,上海,200444;中国科学院广州地球化学研究所有机地球化学国家重点实验室,广州,510640 |
| 基金项目： | 国家自然科学基金（No.20807026)；国家重点基础研究发展计划（973）项目（No.2008CB418205）；上海市重点学科（No.S30109）；上海大学研究生创新基金（No. SHUCX092258） |
| 摘 要： | 分析测定了上海地区居民经常食用的4种肉类、3种鱼类中多氯联苯(PCBs)的含量与分布特征.同时,应用体外实验(invitrotest)模拟人体胃肠液,测定了PCBs对人体的生物有效性.结果表明,上海地区肉类和鱼类中PCBs含量在51.6～1206.4pg.g-1(以鲜重计)之间,与世界其他国家和地区相比属于较低水平,三～七氯代联苯占主要地位.不同食品中PCBs对人体的生物有效性不同,鱼类中PCBs的生物有效性要显著高于肉类,脂肪含量是重要决定因素之一.最后,结合上海市居民对这几种食品的人均摄入量,对该地区居民PCBs的日平均暴露量进行了评估.结果显示,通过肉类食品的日平均暴露量总和为738.7pg.d-1,而鱼类达到了6173.6pg.d-1,食用同等量的肉类和鱼类,食用鱼类PCBs对人体的暴露量是肉类的20倍. |
| 关 键 词： | 多氯联苯 食品 体外实验 生物有效性 暴露评估 |
| 收稿时间： | 9/17/2009 3:52:14 PM |
| 修稿时间： | 2009/12/11 0:00:00 |
Concentrations and human bioaccessibility of polychlorinated biphenyls in meat and fish in Shanghai |
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| HAN Shuyuan,YU Yingxin,LI Junling,WANG Deqing,WU Minghong,SHENG Guoying and FU Jiamo.Concentrations and human bioaccessibility of polychlorinated biphenyls in meat and fish in Shanghai[J].Acta Scientiae Circumstantiae,2010,30(6):1322-1330. | |
| Authors: | HAN Shuyuan YU Yingxin LI Junling WANG Deqing WU Minghong SHENG Guoying and FU Jiamo |
| Institution: | Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444,Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444,Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444,Shanghai Applied Radiation Institute, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444,1. Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444; 2. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences,,1. Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444; 2. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, and 1. Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444; 2. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, |
| Abstract: | Concentrations and congener distribution profiles of PCBs were determined in four types of meat and three types of fish that are consumed frequently by Shanghai residents. The results showed that the concentrations of PCBs in these foods ranged from 51.6 to 1206.4 pg·g-1 (by wet weight). Tri- to hepta-PCBs were dominant congeners in most of the food samples. The levels of PCB contamination in Shanghai were lower than those in most other countries. In addition, the bioaccessibility of PCBs was investigated using an in vitro test that simulated the digestion process in the human gastrointestinal tract. The results demonstrated that the bioaccessibility of PCBs was higher in fish than in meat. Fat content was one of the most important factors influencing the bioaccessibility of PCBs. Finally, the average exposure of PCBs was evaluated for Shanghai residents considering the per capita intake of these foods. The results indicated that the average daily intake of PCBs through fish and meat was 6173.6 and 738.7 pg·d-1, respectively. The exposure to PCBs was 20-fold higher through intake of fish than meat, when the same amounts of fish and meat were consumed. |
| Keywords: | PCBs food in vitro test bioaccessibility exposure assessment |
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