Two-compartment model of radionuclide accumulation into marine organisms. I. Accumulation from a medium of constant activity

The interpretation of kinetics of radionuclide accumulation into biological organisms can be performed by using the well-known multicompartment models. The application of a two-compartment model in the interpretation of radionuclide accumulation into marine organisms, when this does not markedly deplete the medium, is considered. It has been found that most of the loss experiments cannot be interpreted without the use of uptake data. The agreement between the uptake and loss parameters is discussed. Explicit expressions for different kinds of two-compartment models are evaluated. The interpretation of irreversible and other special cases is proposed.