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Erroneous production of PAPP-A kits: the impact of a downward shift in PAPP-A concentration on the test performance of first-trimester combined screening for Down syndrome |
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| Authors: | P N A C M van Heesch Y B de Rijke J A M Laudy H I J Wildschut |
| Institution: | 1. Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Center, Rotterdam, The Netherlands;2. Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prenatal Centre Rijnmond, Star Medical Diagnostic Centre, Rotterdam, The Netherlands;3. Prenatal Centre Rijnmond, Star Medical Diagnostic Centre, Rotterdam, The Netherlands Foundation for Prenatal Screening in the southwest of the Netherlands, Rotterdam, The Netherlands.;4. Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Center, Rotterdam, The Netherlands Foundation for Prenatal Screening in the southwest of the Netherlands, Rotterdam, The Netherlands. |
| Abstract: | |
| Keywords: | β-hCG biochemical screening Down syndrome first-trimester screening NT PAPP-A |